Treating invasive aspergillosis in patients with hematologic malignancy: diagnostic-driven approach versus empiric therapies
نویسندگان
چکیده
منابع مشابه
Comparing Diagnostic-Driven Approaches to Empiric Therapy in the Treatment of Invasive Aspergillosis in Patients with Hematologic Malignancy
165. Outcomes Comparing Initial Short vs Long Course Echinocandin Therapy in Patients with Candidemia Caused by Fluconazole Susceptible Strains Jennifer L. Small-Saunders, MD, PhD; Angela Loo, PharmD BCPS (AQ-ID); Deborah Theodore, MD; Amrita Singh, PharmD; Magdalena Sobieszczyk, MD, MPH and Christine J. Kubin, PharmD BCPS (AQ-ID); Medicine, Columbia University Medical Center, New York, New Yor...
متن کاملGranulocyte transfusions in hematologic malignancy patients with invasive pulmonary aspergillosis: outcomes and complications.
BACKGROUND Granulocyte transfusions (GTXs) have been used successfully as an adjunctive treatment option for invasive infections in some neutropenic patients with underlying hematologic malignancy (HM). PATIENTS AND METHODS We sought to determine the impact of GTX as an adjunct to antifungal therapy in 128 patients with HM and prolonged neutropenia (≥14 days) with a proven or probable invasiv...
متن کاملserum galactomannan and diagnosis of invasive aspergillosis in patients with hematologic malignancies, blood and marrow transplantation
introduction: invasive aspergillosis is a major cause of morbidity and mortality in hematologic malignant patients which have received intensive cytotoxic therapy or undergone blood and marrow transplantation (bmt). early clinical and radiological diagnosis of ia is almost impossible and so mortality is very high. the main purpose of our study was to assay the diagnostic value of serum galactom...
متن کاملPrognosis of Invasive Pulmonary Aspergillosis in Patients with Hematologic Diseases in Korea
BACKGROUND The aim of this study was to investigate therapeutic outcomes and assess factors associated with therapeutic outcomes in hematologic patients with invasive pulmonary aspergillosis (IPA). METHODS We analyzed all consecutive cases of IPA in adults with hematologic diseases from January 2008 to January 2009 at a Catholic Hematopoietic Stem Cell Transplantation (HSCT) Center in Seoul, ...
متن کاملEconomic Comparison of an Empirical Versus Diagnostic-Driven Strategy for Treating Invasive Fungal Disease in Immunocompromised Patients.
PURPOSE Patients with persistent or recurrent neutropenic fevers at risk of invasive fungal disease (IFD) are treated empirically with antifungal therapy (AFT). Early treatment using a diagnostic-driven (DD) strategy may reduce clinical and economic burdens. We compared costs and outcomes of both strategies from a UK perspective. METHODS An empirical strategy with conventional amphotericin B ...
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ژورنال
عنوان ژورنال: BMC Infectious Diseases
سال: 2018
ISSN: 1471-2334
DOI: 10.1186/s12879-018-3584-9